摘要：2025年4月4日，据欧盟食品安全局（EFSA）消息，应欧盟委员会要求，欧盟动物饲料添加剂和产品（FEEDAP）研究小组就谷氨酸棒杆菌CGMCC 7.453发酵生产的L-赖氨酸硫酸盐（L-lysine sulfate）作为所有动物饲料添加剂的安全性和有效性发表

核心提示：2025年4月4日，据欧盟食品安全局（EFSA）消息，应欧盟委员会要求，欧盟动物饲料添加剂和产品（FEEDAP）研究小组就谷氨酸棒杆菌CGMCC 7.453发酵生产的L-赖氨酸硫酸盐（L-lysine sulfate）作为所有动物饲料添加剂的安全性和有效性发表科学意见。……（世界食品网-www.shijieshipin.com）

2025年4月4日，据欧盟食品安全局（EFSA）消息，应欧盟委员会要求，欧盟动物饲料添加剂和产品（FEEDAP）研究小组就谷氨酸棒杆菌CGMCC 7.453发酵生产的L-赖氨酸硫酸盐（L-lysine sulfate）作为所有动物饲料添加剂的安全性和有效性发表科学意见。
经过评估，专家小组认为该添加剂对目标物种、消费者和环境是安全的。评估中的添加剂被认为是所有非反刍动物物种氨基酸L-赖氨酸的有效来源。为了使补充的L-赖氨酸对反刍动物和非反刍动物同样有效，需要防止其在瘤胃中降解。部分原文报道如下：

Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on L-lysine sulfate produced by fermentation with a genetically modified strain of Corynebacterium glutamicum (CGMCC 7.453) when used as a nutritional additive in feed for all animal species. The active substance is L-lysine. The FEEDAP Panel concluded that the production strain qualifies for the qualified presumption of safety (QPS) approach to safety assessment; therefore, L-lysine sulfate produced with C. glutamicum CGMCC 7.453 does not pose any safety concern associated with the production strain. L-Lysine sulfate produced with C. glutamicum CGMCC 7.453 is considered safe for the target species. The FEEDAP Panel has concerns on the use of L-lysine sulfate in water for drinking. When using L-lysine sulfate, the background sulfur/sulfate content in the compound feed should be taken into account. L-Lysine sulfate produced with C. glutamicum CGMCC 7.453 is safe for the consumer and for the environment. based on the information provided in the safety data sheet of the additive under assessment, the FEEDAP Panel concludes that the additive should be considered irritant to skin, eyes and the respiratory tract, and that any exposure to the additive is a risk. L-Lysine sulfate is considered an efficacious source of the essential amino acid L-lysine for non-ruminant animal species. For the supplemental L-lysine to be as efficacious in ruminants as in non-ruminant species, it would require protection against degradation in the rumen.

来源：食品世界