摘要：目前帕金森病的热点机制又有新进展。有研究强调了lysosome生物学在帕金森病发病中的作用，特别是与家族性和散发性帕金森病相关的基因如何与溶酶体功能有关。有研究探讨了大脑前后系统在认知功能中的作用，以及帕金森病患者认知障碍与脑部特定神经递质系统的关联。有研究指
目前帕金森病的热点机制又有新进展。有研究强调了lysosome生物学在帕金森病发病中的作用，特别是与家族性和散发性帕金森病相关的基因如何与溶酶体功能有关。有研究探讨了大脑前后系统在认知功能中的作用，以及帕金森病患者认知障碍与脑部特定神经递质系统的关联。有研究指出嗅觉功能改变作为早期帕金森病的生物标志，并讨论了其潜在的病理机制和治疗靶点。为此，选择本刊学者2023-2024年发表的帕金森病发病机制的热点综述文章3篇，推荐读者阅读。
(1) Roles of neuronal lysosomes in the etiology of Parkinson's disease
神经元溶酶体在帕金森病病因中的作用
Mattia Volta 1
Institute for Biomedicine, Eurac Research, Bolzano, Italy.
引用本文：
Volta M. Roles of neuronal lysosomes in the etiology of Parkinson's disease. Neural Regen Res. 2024;19(9):1981-1983.
正文链接：
(2)A review of the neurotransmitter system associated with cognitive function of the cerebellum in Parkinson's disease
与帕金森病小脑认知功能相关的神经递质系统综述
Xi Chen 1, Yuhu Zhang 2
1Department of Neurology, Guangdong Neuroscience Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou; Shantou University Medical College, Shantou, Guangdong Province, China.
2Department of Neurology, Guangdong Neuroscience Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong Province, China.
引用本文：
Chen X, Zhang Y. A review of the neurotransmitter system associated with cognitive function of the cerebellum in Parkinson's disease. Neural Regen Res. 2024;19(2):324-330.
正文链接：
(3) Olfactory dysfunction and its related molecular mechanisms in Parkinson's disease
帕金森病的嗅觉功能障碍及其相关分子机制
Yingying Gu 1, Jiaying Zhang 1, Xinru Zhao 1, Wenyuan Nie 1, Xiaole Xu 1, Mingxuan Liu 1, Xiaoling Zhang 1
1College of Pharmacy, Nantong University, Nantong, Jiangsu Province, China.
引用本文：
Gu Y, Zhang J, Zhao X, Nie W, Xu X, Liu M, Zhang X. Olfactory dysfunction and its related molecular mechanisms in Parkinson's disease. Neural Regen Res. 2024;19(3):583-590.
正文链接：
来源：中国神经再生研究杂志
