摘要：第47届圣安东尼奥乳腺癌研讨会（SABCS）将于当地时间2024年12月10日至13日在美国得克萨斯州圣安东尼奥举行。SABCS是全球最大的乳腺癌领域盛会，来自102个国家的超过1万名注册参会者将在为期四天的会议中展示1886篇被接受的论文摘要。肿瘤瞭望特别整

编者按：第47届圣安东尼奥乳腺癌研讨会（SABCS）将于当地时间2024年12月10日至13日在美国得克萨斯州圣安东尼奥举行。SABCS是全球最大的乳腺癌领域盛会，来自102个国家的超过1万名注册参会者将在为期四天的会议中展示1886篇被接受的论文摘要。肿瘤瞭望特别整理中国专家被收录的壁报内容，以飨读者。（注：因官网未公布详细作者单位，如有遗漏或错误，欢迎留言指正。）

Poster Session 1

日期：12月11日

时间：12:30～2:00 p.m

地点：Halls 2-3

P1-01-04：EPLIN and EPLIN responsive protein APOC3 in breast cancer

EPLIN及其应答蛋白APOC3在乳腺癌中的作用

报告作者：Cai Wang

P1-02-12: Prospective phase II study on the efficacy and safety of hetrombopag for the treatment of cancer therapy-induced thrombocytopenia in patients with breast cancer

在乳腺癌患者中应用海曲泊帕治疗癌症治疗诱导的血小板减少症的有效性和安全性的前瞻性II期研究

报告作者：Hanfang Jiang

P1-02-18: Cancer-Associated Fibroblast-Mediated Suppression of T Cell Activity as a mechanism of Resistance to Immunoradiotherapy in Breast Cancer

癌症相关成纤维细胞介导的T细胞活性抑制作为乳腺癌免疫放疗抵抗的机制

报告作者：Rongrong Wu

P1-04-04: evelopment and validation of a nomogram for axillary lymph node metastasis risk in breast cancer

乳腺癌腋窝淋巴结转移风险列线图的建立和验证

报告作者：Xiaoyun Mao

P1-04-12: Optimizing Tolerability of Pyrotinib in HER2-Positive EarlyStage High-Risk Breast Cancer: A Multicenter, Randomized, ThreeCohort Study

优化吡咯替尼治疗HER2阳性早期高危乳腺癌的耐受性：一项多中心、随机、三队列研究

报告作者：Qiao Cheng

P1-04-22: Loss of SMAD4 Drives Breast Cancer Invasion and Metastasis through E2F1-Mediated Activation of the PEG10-ERK Axis

SMAD4缺失通过E2F1介导的PEG10-ERK轴激活驱动乳腺癌的侵袭和转移

报告作者：Dan Shu

P1-04-25: Fast and accurate detection of tumor-immune cell interactions with deep learning

利用深度学习快速准确地检测肿瘤-免疫细胞相互作用

报告作者：Huiping Liu

P1-05-07: Expression of ATP6AP2 in clinical breast cancer and the prognostic and therapeutic value in ERBB2 subtype of breast cancer

ATP6AP2在临床乳腺癌中的表达及其在ERBB2亚型乳腺癌中的预后和治疗价值

报告作者：Jia Tong

P1-05-24: Biomarkers and Spatial Determinants of SHR-A1811 Efficacy in Neoadjuvant Treatment for HER2-Positive Breast Cancer

SHR-A1811在HER2阳性乳腺癌新辅助治疗中疗效的生物标志物和空间决定因素

报告作者：Zhi-Ming Shao

P1-05-27: Analytical comparison of tissue-based next-generation sequencing assays for the detection of PIK3CA, AKT1, and PTEN tumor alterations in breast cancer

基于组织的二代测序检测乳腺癌中PIK3CA、AKT1和PTEN肿瘤改变的分析比较

报告作者：Xiaodun Li

P1-06-04: Psychological stress and its correlations to patients with acute lymphedema after breast cancer surgery

心理应激与乳腺癌术后急性淋巴水肿的相关性研究

报告作者：Li-Chen Tang

P1-06-06: Oral cyclophosphamide-induced hemorrhagic cystitis from metronomic Cyclophosphamide/Methotrexate/5-Fluorouracil for treatment of synchronous bilateral breast cancer – A case report

口服环磷酰胺导致出血性膀胱炎：一例应用节拍化疗方案环磷酰胺/甲氨蝶呤/5-氟尿嘧啶治疗同期双侧乳腺癌的病例报告

报告作者：Jina Yun

P1-06-24: Single-cell RNA sequencing reveals the role of HSPA1B+ immune cells in breast cancer microenvironment remodeling during neoadjuvant chemotherapy

单细胞RNA测序揭示HSPA1B+免疫细胞在乳腺癌新辅助化疗微环境重塑中的作用

报告作者：Zihan Zhai

P1-06-29: Targeting NRP1 reduces triple-negative breast cancer lung metastasis and improves immunotherapy efficacy

靶向NRP1可降低三阴性乳腺癌肺转移，并提高免疫治疗疗效

报告作者：Zhuxi Duan

P1-07-20: Mechanism of miR-221-3p/PARP1 regulating the progression of triple-negative breast cancer through the NF-κB pathway

miR-221-3p/PARP1通过NF-κB通路调控三阴性乳腺癌进展的机制

报告作者：Qianqian Lei

P1-07-21: Efficacy of CDK4/6 Inhibitor Abemaciclib in Metastatic Triple-Negative Breast Cancer

CDK4/6抑制剂阿贝西利治疗转移性三阴性乳腺癌的疗效

报告作者：Chuling Zhuang

P1-07-25: E3 ubiquitin-protein ligase RNF40 promotes triplenegative breast cancer progression and metastasis by promoting TRIM28 expression and stabilizing TWIST1 protein

E3泛素蛋白连接酶RNF40通过促进TRIM28表达和稳定TWIST1蛋白促进三阴性乳腺癌的进展和转移

报告作者：Junjiang Fu

P1-07-28: Real-World Study on Efficacy and Safety of SG Alone and Combined with Immunotherapy in Metastatic Triple Negative Breast Cancer Patients

SG单药及联合免疫治疗转移性三阴性乳腺癌患者的疗效和安全性的真实世界研究

报告作者：Jianli Zhao

P1-08-02: HIF-1-dependent expression of integrin β3 incorporated into extracellular vesicles promotes metastasis of breast cancer cells to the brain

HIF-1依赖的整合素β3表达整合入细胞外囊泡中，促进乳腺癌细胞向脑的转移

报告作者：Yongkang Yang

P1-08-05: The mechanism of FOXO3a in coping with oxidative stress to promote TNBC progression

FOXO3a应对氧化应激促进TNBC进展的机制

报告作者：Manqing Cao

P1-08-21: Synchronous female breast cancer and follicular lymphoma in a single patient: A case report

女性乳腺癌同时合并滤泡性淋巴瘤一例报告

报告作者：Zijun Zhao

P1-09-05: Simultaneous 3D Mapping of RNA and Protein to Advance Personalized Medicine in Breast Cancer

同时进行RNA和蛋白质的3D绘图以推进乳腺癌的个体化治疗

报告作者：Yue Li

P1-09-11: Machine Learning based analysis in chemotherapy resistant triple negative breast cancer

基于机器学习的化疗耐药三阴性乳腺癌分析

报告作者：Dongling Wu

P1-09-24: Cancer cell-derived exosomal miR-20a-5p inhibits CD8+ T-cell function and confers anti-programmed cell death 1 therapy resistance in triple-negative breast cancer

三阴性乳腺癌细胞衍生的外泌体miR-20a-5p抑制CD8+ T细胞功能并导致抗程序性细胞死亡1治疗耐药

报告作者：XIANGDONG BAI

P1-10-17: HER2+ breast cancer diagnosed in the 2nd trimester of pregnancy

妊娠中期诊断的HER2+乳腺癌

报告作者：Shiliang Zhang

P1-11-01: Immune Infiltration Correlates with Transcriptomic Subtypes in Primary ER+ Invasive Lobular Breast Cancer

原发性ER+浸润性小叶乳腺癌的免疫浸润与转录组亚型相关

报告作者：Fangyuan Chen

P1-11-07: Associations between Breast Cancer Index Classifications and MSK-IMPACT Genomic Profiles in HR+/HER2- Breast Cancer

HR+/HER2-乳腺癌中乳腺癌指数分类与MSK-IMPACT基因组谱的相关性

报告作者：Hong Zhang

P1-11-11: Pathological Complete Response and Survival Outcomes ofSingle Hormone Receptor-Positive/HER2-Negative Breast Cancer after Neoadjuvant Treatment and Further analysis of its Intrinsic Biological Features and Immune Landscape.

新辅助治疗后单激素受体阳性/HER2阴性乳腺癌的病理完全缓解及生存结局，以及对其内在生物学特征和免疫图谱的进一步分析

报告作者：Lei Ji

P1-11-12: Early-stage HR+/HER2- breast cancer patients under 50 years old with a low-risk identified by the 70-gene signature (MammaPrintTM) could benefit from ovarian function suppression: A real-world study in China.

基于70基因特征（MammaPrintTM）鉴定为低风险的50岁以下早期HR+/HER2-乳腺癌患者可从卵巢功能抑制中获益：一项中国真实世界研究

报告作者：Weijuan Jia

P1-11-13: Development and Validation of a Deep Learning Model for HR+/HER2- Early-stage Breast Cancer Recurrence Prediction (HERPAI) using Conventional Clinical and Pathological Data: A Realworld Study in Chinese Population

基于常规临床和病理数据构建并验证用于HR+/HER2-早期乳腺癌复发预测的深度学习模型（HERPAI）：一项针对中国人群的真实世界研究

报告作者：Ruixin Pan

P1-12-09: Real-world prescribing patterns and outcomes of CDK4/6 inhibitors in elderly patients with metastatic HR+/HER2- breast cancer

CDK4/6抑制剂在老年转移性HR+/HER2-乳腺癌患者中的真实世界处方模式和结局

报告作者：Xiao-Wei Tan

P1-12-26: Clinical Case Vignette - Molecular PET Imaging to Guide Selection for Endocrine Therapy in Estrogen-Receptor Positive Metastatic Breast Cancer

临床病例简述——分子PET成像指导雌激素受体阳性转移性乳腺癌内分泌治疗的选择

报告作者：Wenhui Zhou

P1-12-27: Clinical Case Vignette: Estrogen Receptor Targeting PET Imaging to Monitor Treatment Response to Endocrine Therapy in Lobular Breast Cancer

来源：肿瘤瞭望