NRR热点综述：视网膜疾病的神经保护策略研究

摘要：视网膜疾病如糖尿病视网膜病变和视网膜变性等疾病可导致视觉功能损害。目前，视网膜疾病的神经保护策略偏向于探索如牛磺酸、巨噬细胞迁移抑制因子及生长抑素等分子的神经保护作用及其在调节炎症、抗氧化、抑制细胞凋亡等方面的机制。研究者关注如何通过这些分子进行早期干预，以预

视网膜疾病如糖尿病视网膜病变和视网膜变性等疾病可导致视觉功能损害。目前，视网膜疾病的神经保护策略偏向于探索如牛磺酸、巨噬细胞迁移抑制因子及生长抑素等分子的神经保护作用及其在调节炎症、抗氧化、抑制细胞凋亡等方面的机制。研究者关注如何通过这些分子进行早期干预，以预防或延缓视网膜病变的进展，保护视力。

为此，选择本刊学者2024年发表的视网膜疾病的神经保护策略研究的热点综述文章3篇，推荐读者阅读。

（1）Taurine: a promising nutraceutic in the prevention of retinal degeneration

牛磺酸：预防视网膜变性的有效营养素

Diego García-Ayuso 1, Johnny Di Pierdomenico 1, Ana Martínez-Vacas 1, Manuel Vidal-Sanz 1, Serge Picaud 2, María P Villegas-Pérez 1

1 Grupo de Investigación Oftalmología Experimental, Departamento de Oftalmología, Optometría, Otorrinolaringología y Anatomía Patológica, Facultad de Medicina, Universidad de Murcia, Instituto Murciano de Investigación Biosanitaria (IMIB), Campus de Ciencias de la Salud, Murcia, España.

2 Sorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France.

引用本文：

García-Ayuso D, Di Pierdomenico J, Martínez-Vacas A, et al. Taurine: a promising nutraceutic in the prevention of retinal degeneration. Neural Regen Res. 2024;19(3):606-610.

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（2）The roles of macrophage migration inhibitory factor in retinal diseases

巨噬细胞迁移抑制因子在视网膜疾病中的作用

Hongbing Zhang 1, Xianjiao Zhang 2, Hongsong Li 3, Bing Wang 3, Pei Chen 3, Jiamin Meng 3

1 Shaanxi Institute of Ophthalmology, Xi'an; Department of Ophthalmology, First Affiliated Hospital of Northwest University, Xi'an, Shaanxi Province, China.

2 Department of Pathology, First Affiliated Hospital of Northwest University, Xi'an, Shaanxi Province, China.

3 Department of Ophthalmology, First Affiliated Hospital of Northwest University, Xi'an, Shaanxi Province, China.

引用本文：

Zhang H, Zhang X, Li H, et al. The roles of macrophage migration inhibitory factor in retinal diseases. Neural Regen Res. 2024;19(2):309-315.

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（3）On implications of somatostatin in diabetic retinopathy

体生长抑素对糖尿病视网膜病变的影响

Yanhong Fang 1, Qionghua Wang 1, Youjian Li 2, Li Zeng 3, Jian Liu 4, Kepeng Ou 2

1 Department of Ophthalmology, Chongqing University Jiangjin Hospital, Chongqing, China.

2 College of Pharmacy, National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, IATTI, Chongqing University of Arts and Sciences, Chongqing, China.

3 Shandong Provincial Hospital, Shandong Laboratory Animal Center, Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong Province, China.

4 Academic Unit of Ophthalmology, Bristol Medical School, University of Bristol, Bristol, UK.

引用本文：

Fang Y, Wang Q, Li Y, et al. On implications of somatostatin in diabetic retinopathy. Neural Regen Res. 2024;19(9):1984-1990.

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